W A Alrefai Selected Research

MK-886

1/2005	Reactive oxygen species and redox-induced programmed cell death due to MK 886: cells ("soil") "trump" agent ("seed").
9/2004	Acute changes in U937 nuclear Ca2+ preceding type 1 "apoptotic" programmed cell death due to MK 886.
4/2002	Increased cytosol Ca(2+) and type 1 programmed cell death in Bcl-2-positive U937 but not in Bcl-2-negative PC-3 and Panc-1 cells induced by the 5-lipoxygenase inhibitor MK 886.
7/2000	A genomic response of H-358 bronchiolar carcinoma cells to MK 886, an inhibitor of 5-lipoxygenase, assessed with a cDNA array.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

W A Alrefai Research Topics

Disease

2	Myeloid Leukemia (Leukemia, Myelocytic) 01/2005 - 04/2002
2	Pancreatic Neoplasms (Pancreatic Cancer) 09/2004 - 01/2002
2	Neoplasms (Cancer) 01/2002 - 07/2000
1	Uterine Cervical Neoplasms (Cancer of the Cervix) 01/2005
1	Adenocarcinoma 02/2004
1	Congenital chloride diarrhea 11/2001
1	Adenoma (Adenomas) 11/2001
1	Bronchiolo-Alveolar Adenocarcinoma (Adenocarcinoma, Bronchiolo Alveolar) 07/2000

Drug/Important Bio-Agent (IBA)

4	MK-886IBA 01/2005 - 07/2000
2	Complementary DNA (cDNA)IBA 01/2002 - 07/2000
1	CaspasesIBA 01/2005
1	Lipoxygenase InhibitorsIBA 01/2005
1	Reactive Oxygen Species (Oxygen Radicals)IBA 09/2004
1	Protein Isoforms (Isoforms)IBA 02/2004
1	AnionsIBA 02/2004
1	Butyrates (Butyrate)IBA 02/2004
1	Proteins (Proteins, Gene)FDA Link 04/2002
1	Messenger RNA (mRNA)IBA 01/2002
1	Cisplatin (Platino)FDA LinkGeneric 01/2002
1	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 01/2002
1	Growth Factor ReceptorsIBA 01/2002
1	ChloridesIBA 11/2001
1	Arachidonate 5-Lipoxygenase (5 Lipoxygenase)IBA 07/2000

Therapy/Procedure

2	Therapeutics 01/2002 - 07/2000
1	Drug Therapy (Chemotherapy) 01/2002